Keyword Analysis & Research: zrsr2 mds


Keyword Analysis

Keyword CPC PCC Volume Score Length of keyword
zrsr2 mds0.750.421429
zrsr20.140.11307805
mds1.2114350733

Keyword Research: People who searched zrsr2 mds also searched

Keyword CPC PCC Volume Score
zrsr2 mds0.830.5658580
zrsr2 mutation1.760.9259729
zrsr2 mutation mds0.880.5852880
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Choose at least 2 and not exceed 5 keywords


Search Results related to zrsr2 mds on Search Engine

  • Concurrent Zrsr2 mutation and Tet2 loss promote ... - Nature

    nature.com

    https://www.nature.com/articles/s41375-022-01674-2

    WebAug 27, 2022 · Here, we show that concurrent mutations in Zrsr2 and Tet2 promote MDS via dysregulation of gene expression and alternative splicing. We detect a disruption in myelo …

    DA: 81 PA: 87 MOZ Rank: 72

  • ZRSR2 Mutation Induced Minor Intron Retention Drives MDS and …

    ashpublications.org

    https://ashpublications.org/blood/article/136/Supplement%201/10/470256/ZRSR2-Mutation-Induced-Minor-Intron-Retention

    WebNov 5, 2020 · To understand the mechanistic basis by which ZRSR2 loss causes aberrant HSC self-renewal, we quantified transcriptome-wide splicing patterns in MDS patients. ZRSR2 … Author: Daichi Inoue, Daichi Inoue, Jacob T. Polaski, Justin Taylor, Pau Castel, Sisi Chen, Susumu Kobayashi... Publish Year: 2020

    Author: Daichi Inoue, Daichi Inoue, Jacob T. Polaski, Justin Taylor, Pau Castel, Sisi Chen, Susumu Kobayashi...

    Publish Year: 2020

    DA: 15 PA: 63 MOZ Rank: 28

  • ZRSR2 Mutations Cause Dysregulated RNA Splicing in MDS

    ashpublications.org

    https://ashpublications.org/blood/article/124/21/4609/94026/ZRSR2-Mutations-Cause-Dysregulated-RNA-Splicing-in

    WebDec 6, 2014 · Mutations in ZRSR2are more prevalent in MDS subtypes without ring sideroblasts and chronic myelomonocytic leukemia (CMML) and are associated with … Author: Vikas Madan, Deepika Kanojia, Li Jia, Ryoko Okamoto, Aiko Sato-Otsubo, Aiko Sato-Otsubo, Alexander K... Publish Year: 2014

    Author: Vikas Madan, Deepika Kanojia, Li Jia, Ryoko Okamoto, Aiko Sato-Otsubo, Aiko Sato-Otsubo, Alexander K...

    Publish Year: 2014

    DA: 9 PA: 22 MOZ Rank: 91

  • Spliceosomal Factor Mutations and Mis-splicing in MDS - PMC

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078562/

    WebZRSR2 mutations are present in MDS patients at a frequency of 3–8%. But ZRSR2 occurs less frequently (<2%) of patients with AML [ 3 , 61 ]. Additionally, ZRSR2 expression is … Author: Courtney E. Hershberger, Noah J. Daniels, Richard A. Padgett DOI: 10.1016/j.beha.2020.101199 Publish Year: 2020 Published: 2020/09

    Author: Courtney E. Hershberger, Noah J. Daniels, Richard A. Padgett

    DOI: 10.1016/j.beha.2020.101199

    Publish Year: 2020

    Published: 2020/09

    DA: 36 PA: 79 MOZ Rank: 37

  • Minor intron retention drives clonal hematopoietic …

    nature.com

    https://www.nature.com/articles/s41588-021-00828-9

    WebApr 12, 2021 · Consistent with the effect of ZRSR2 mutations in MDS on splicing, hematopoietic precursors (lineage-negative c-Kit + cells) from … Author: Daichi Inoue, Jacob T. Polaski, Justin Taylor, Pau Castel, Sisi Chen, Susumu Kobayashi, Susumu Kobay... Publish Year: 2021

    Author: Daichi Inoue, Jacob T. Polaski, Justin Taylor, Pau Castel, Sisi Chen, Susumu Kobayashi, Susumu Kobay...

    Publish Year: 2021

    DA: 43 PA: 54 MOZ Rank: 1

  • Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair …

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831459/

    WebFeb 2, 2022 · ZRSR2 belongs to the minor subset of X chromosome genes that escape X inactivation silencing and is biallelically expressed in female cells . The finding that …

    DA: 27 PA: 50 MOZ Rank: 91

  • Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic ne…

    nature.com

    https://www.nature.com/articles/s41375-022-01674-2

    DA: 85 PA: 100 MOZ Rank: 18

  • The functional mechanisms of mutations in myelodysplastic …

    nature.com

    https://www.nature.com/articles/s41375-019-0617-3

    WebOct 31, 2019 · Focusing on the most frequently mutated pathways, 65% of MDS patients harbored mutations in RNA splicing ( SF3B1, SRSF2, U2AF1, ZRSR2) [ 12 ], followed by 47% …

    DA: 28 PA: 22 MOZ Rank: 42

  • Zrsr2 Is Essential for the Embryonic Development and Splicing of …

    nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501576/

    WebSep 14, 2022 · ZRSR2 is an essential component of both the major and minor spliceosomes and is frequently mutated in hematopoietic disorders, particularly MDS. Recent studies …

    DA: 14 PA: 35 MOZ Rank: 28

  • Genetics of MDS | Blood | American Society of Hematology

    ashpublications.org

    https://ashpublications.org/blood/article/133/10/1049/272730/Genetics-of-MDS

    WebMar 7, 2019 · Mutations in some genes are significantly enriched in sAML compared with high-risk MDS, including FLT3, NPM1, NRAS, PTPN11, WT1, IDH1, and IDH2 (type I genes), while …

    DA: 83 PA: 65 MOZ Rank: 19